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estradiol cypionate 5 mg/mL Medicare Part D Coverage

Brand name: Depo-Estradiol
Dosage form
INJECTION
Route
INTRAMUSCULAR
44%
of Medicare Part D plans
cover estradiol cypionate
2,407 of 5,530 plans
3.8
Avg. formulary tier
$44.00
Median 30-day copay
$0.00–$88.00
Copay range

Formulary Tier Distribution

How Medicare Part D plans classify estradiol cypionate. Lower tiers = lower copays.

Tier 1 - Preferred Generic 0%
9 plans • avg $0.00/mo
Tier 2 - Generic 5%
115 plans • avg $3.33/mo
Tier 3 - Preferred Brand 9%
223 plans • avg $22.65/mo
Tier 4 - Non-Preferred Drug 86%
2,060 plans • avg $0.62/mo

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estradiol cypionate Medicare Coverage by State

Coverage rates and average costs vary significantly by state. Click a state to see the specific plans available there.

Frequently Asked Questions about estradiol cypionate

44% of Medicare Part D plans cover estradiol cypionate. It is most commonly placed on Tier 4. Coverage varies by plan and geographic area.

The median 30-day copay for estradiol cypionate on Medicare Part D is $44.00 at a preferred pharmacy. Costs range from $0.00 to $88.00 depending on the plan.

estradiol cypionate is placed on Tier 4 by most Medicare Part D plans. Lower tier numbers generally mean lower copays.

0% of plans require prior authorization for estradiol cypionate. Prior authorization means your doctor must confirm the drug is medically necessary before the plan will cover it.

Coverage statistics based on CMS formulary data for plan year 2026. Data updated regularly. Methodology →